Akhila Sahoo
University of Hyderabad, Hyderabad
Prof. Akhila Sahoo has been Professor of Chemistry at the University of Hyderabad since 2016. He completed his PhD at the National Chemical Laboratory, Pune, India. He did his postdoctoral research at Kyoto University, Japan. His research interests are transition-metal-catalyzed organic transformations, Lewis-acid-catalyzed organic transformations and high-energy materials. He was elected Fellow of IASc in 2021.
Session 2C: Lectures by Fellows/Associates
Chairperson: Rajesh K Srivastava, BHU, Varanasi
Sustainable Synthetic Organic Chemistry on Pharmaceutical Innovation
Tetrasubstituted olefins and heterocycles are fundamental building blocks present in many natural products, pharmaceuticals, agrochemicals, and electron-transport materials. Tamoxifen, a tricyclicethylene moiety, is an important drug candidate.The regioselective difunctionalization of unsymmetrical alkynes provides facile access to highly substituted olefins, like Tamoxifen. The cyclization and annulation reactions of alkynes offer an attractive means to access various heterocyclic compounds. This multi-component one-pot synthetic protocol could be sustainable and cost-effective when compared with multi-step methods. This presentation will feature strategies to design synthetic routes enabling tetrasubstituted olefins and cyclic heterocycles.